This list is not exhaustive, but does cover the most important changes.
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Study Tags
Study Tags are now available, replacing Playlists in the previous versions. In the Admin section, (1) Tags can be configured by a properly privileged user. On the Study tab (2), one or more tags can be assigned to a specific study.
User configuration (Admin and User)
User configuration has more options for icons, colors and ways to create a signature
Link to comprehensive Site Admin Training